https://mayomeds.com/klonopin-vs-clonidine/
Klonopin (clonazepam) is a benzodiazepine prescribed for panic disorder, anxiety, and certain seizure conditions. It works by enhancing GABAergic inhibition in the brain, producing sedation, anticonvulsant, and muscle‑relaxing effects. Onset is within an hour, lasting around 8 – 12 hours. Common side effects include drowsiness, coordination issues, memory problems, and risk of dependence and withdrawal with long‑term use Clonidine is a centrally acting α₂‑adrenergic agonist used for hypertension, ADHD, withdrawal support, and occasionally anxiety. It lowers blood pressure and calms physical arousal by inhibiting norepinephrine release. Effects start within an hour and may persist 6–8 hours. Side effects include sedation, dry mouth, dizziness, hypotension—though it does not cause psychological dependence.
