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In particular, pregabalin binds to calcium channels in the central nervous system, reducing the release of neurotransmitters like glutamate, norepinephrine, and substance P, which are involved in pain signalling and anxiety. Pregabalin is a prescription drug that belongs to the class of medications known as gabapentinoids, which work by calming overactive nerves in the brain and spinal cord. Pregabalin is primarily used to treat neuropathic pain, epilepsy, and generalised anxiety disorder.
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