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Tapentadol, sold under brand names like Nucynta and Palexia, is a prescription medication used to treat moderate to severe pain. It is a synthetic opioid that works by binding to the brain’s mu-opioid receptors and also by inhibiting the reuptake of norepinephrine, a neurotransmitter involved in pain signaling. This dual mechanism of action makes tapentadol effective for pain relief while potentially reducing some of the side effects associated with traditional opioids.
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